Hurricane Matthew's strong winds and high flood waters have taken the lives of more than 100 people across the Caribbean and continue to threaten millions more.
For the latest track/forecast of Hurricane Matthew, visit the National Hurricane Center.
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It is the biggest threat to the Atlantic coast in more than a decade.
Haiti took the worst of the storm, with a death toll of at least 114 people - a number that is expected to climb as more victims are found. Most of those who died were impoverished Haitians who either didn't know the storm was coming or couldn't evacuate in time.
Catastrophic winds of more than 140 miles per hour are barreling their way towards the United States' lower east coast and is expected to move up the coast - triggering states of emergency along its expected path.
Higways are filled with vehicles belonging to people evacuating and hoping to find a safe place escape the wrath of Hurricane Matthew.
"The storm has already killed people. We should expect the same impact in Florida," Gov. Rick Scott said.
It was expected to devastate Miami, but millions of people were spared when the hurricane moved north towards Jacksonville and Cape Canaveral.
"We were lucky this time," Miami-Dade Mayor Carlos Gimenez said.
Although Miami may not face the brunt of the storm, thousands of flights in and out of Florida are cancelled for the weekend. Cruise lines are also rerouting their courses to stay out of Matthew's path.
Meteorologists expect the storm to hover close to Georgia and South Carolina over the weekend before moving out the sea.
It could still be dangerous, though. Once Matthew heads out to sea, the hurricane can swing back around and strike southern Florida again on Tuesday. By that time the storm would be weaker, but still deadly.
"The second landfall, if it does happen, is considerably less of a worry than what's going to occur in the next day or two," says private meteorologist Ryan Maue at Weather Bell Analytics. "Florida is going to take a lot of the punch out of it when it hits land the first time."